Gene interactions and pathways from curated databases and text-mining

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TSC1 — WNT3

Text-mined interactions from Literome

Mak et al., Am J Pathol 2005 (Angiomyolipoma...) : Further, the interaction between TSC1/TSC2 and components of the beta-catenin degradation complex was dependent on Wnt stimulation such that binding of tuberin to GSK3 and Axin was reduced in the presence of Wnt whereas the tuberin Dishevelled interaction was increased
Vigneron et al., Cardiovasc Res 2011 (Disease Models, Animal...) : A downstream target might be mammalian target of rapamycin (mTOR) since Wnt can impair tuberous sclerosis complex-2 (TSC2) phosphorylation by inhibiting GSK-3ß