Zhang et al., Biochem Biophys Res Commun 2010
(Inflammation) :
Our study indicates that p65/RelA mediates the TNF-alpha induced elevated expression of SIRT1 in VSMCs, shedding new light on the regulation of SIRT1 under inflammatory conditions
Breitenstein et al., Cardiovasc Res 2011
(Disease Models, Animal...) :
Sirt1 inhibition further enhanced TF mRNA expression, TF promoter activity, and nuclear translocation as well as DNA binding of the p65 subunit of nuclear factor-kappa B ( NF?B/p65 )
Planavila et al., Cardiovasc Res 2011
(Cardiomegaly...) :
Co-immunoprecipitation studies revealed that overexpression of Sirt1 enhanced PPARa binding to the p65 subunit of NF-?B and led to p65-deacetylation in NCMs