Gene interactions and pathways from curated databases and text-mining

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IGF2 — WNK1

Text-mined interactions from Literome

Vitari et al., Biochem J 2004 (Hypertension...) : Moreover, IGF1 induced phosphorylation of endogenous WNK1 did not occur in PDK1-/- ES ( embryonic stem ) cells, in which PKB is not activated ... In contrast, IGF1 still induced normal phosphorylation of WNK1 in PDK1 ( L155E/L155E ) knock-in ES cells in which PKB, but not S6K ( p70 ribosomal S6 kinase ) or SGK1 ( serum- and glucocorticoid induced protein kinase 1 ), is activated
Wu et al., J Biol Chem 2008 : In rat growth plate chondrocytes, IGF-I induced NF-kappaB-p65 nuclear translocation