◀ Back to CREB1
CREB1 — VIP
Text-mined interactions from Literome
Delgado et al., J Biol Chem 2001
(MAP Kinase Signaling System) :
Second,
VIP/PACAP induce phosphorylation of the
CRE binding protein ( CREB ) and its binding to the CREB binding protein (CBP)
Leceta et al., Ann N Y Acad Sci 2000
(Inflammation) :
VIP/PACAP inhibit iNOS expression through reduction in NFkB and IRF-1 binding, and augment IL-10 by
increasing CREB binding
Masson et al., Mol Cell Biol 1992
:
In contrast to their effects on somatostatin, exogenous
CREB and cPKA do not
activate the
VIP promoter ... Thus, despite coregulation during differentiation and the ability to bind CREB, the somatostatin and
VIP promoters are not coordinately
activated by
CREB in undifferentiated F9 cells
Fernández et al., J Mol Endocrinol 2005
:
IGF-I and
vasoactive intestinal peptide (VIP) regulate cAMP-response element binding protein (
CREB ) -dependent transcription via the mitogen activated protein kinase ( MAPK ) pathway in pituitary cells : requirement of Rap1 ... In summary, we showed that IGF-I and
VIP stimulated MAPK activity and the phosphorylation of
CREB in pituitary cells
Persson et al., Bone 2005
:
In addition,
VIP enhanced the phosphorylation of
CREB , as assessed by both immunocytochemical analysis and Western blot
Hokari et al., Am J Physiol Gastrointest Liver Physiol 2005
:
VIP induced cAMP response element binding protein (
CREB ) /ATF1 phosphorylation, and this was prevented by treatment with inhibitors of either MEK or p38 and by PKA and MSK1 inhibitor H89
Guan et al., Regul Pept 2009
:
VIP increased the
CREB DNA binding activity and expression of the p-CREB that were inhibited by VIP receptor antagonist
Schomerus et al., Cell Tissue Res 1996
:
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide ( PACAP )
induce phosphorylation of the transcription factor
CREB in subpopulations of rat pinealocytes : immunocytochemical and immunochemical evidence ... Immunocytochemical and immunochemical investigations with an antibody against total CREB showed that stimulation with
VIP , PACAP and NE did not
affect the level of
CREB