Gene interactions and pathways from curated databases and text-mining

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MAPK14 — VDR

Text-mined interactions from Literome

Boland et al., Steroids 2002 : However, the activation of MAPK by the hormone was only partially mediated by the VDR and required in addition increased PKC and intracellular Ca ( 2+ )
Qi et al., J Biol Chem 2004 (Colonic Neoplasms) : p38 MAPK activation selectively induces cell death in K-ras mutated human colon cancer cells through regulation of vitamin D receptor
Cordes et al., Anticancer Res 2006 (Breast Neoplasms...) : In conclusion, it seems that the early induction of the MAPK-cascade was independent of the VDR
Wu et al., Cancer Lett 2007 (MAP Kinase Signaling System) : Both sustained ( 3 days ) and transient ( 15min ) 1,25D treatment activated JNK and ERK1/2 MAPK signaling in a nongenomic VDR dependent manner
Xie et al., Med Oncol 2010 (Breast Neoplasms) : These effects were blocked by the MAP kinase blocker PD98059 ( 25 µM ), indicating that MAPK plays a role in VDR and p21 upregulation
Zhang et al., J Cell Physiol 2010 (MAP Kinase Signaling System) : 1,25 ( OH ) ( 2 ) D ( 3 ) -mediated transcription depends upon the VDR and its heterodimeric partner the retinoid X receptor ( RXR ) so we studied whether changes in the VDR-RXR transcription complex occur in response to MAPK activation
Jiang et al., Mol Cell Endocrinol 2012 (MAP Kinase Signaling System) : PMA increased MAPK dependent Sp3 phosphorylation, Sp3-VDR interactions, and Sp3 binding to the hCYP24A1 promoter