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IGF1 — VDR
Text-mined interactions from Literome
Pirskanen et al., Eur J Biochem 1993
(Osteosarcoma) :
The binding of the
vitamin-D receptor (VDR) to its cognate response element is not
affected by
IGF-I
Klaus et al., Kidney Int 1998
:
The studies were undertaken to investigate interaction between these two hormone systems, that is, ( i ) to study effects of 1 alpha, 25 ( OH ) 2D3 on IGF-type 1 receptors ( IGFIR ), on IGF-I stimulated cell replication, colony formation, and on alkaline phosphatase activity ( AP ), and conversely, ( ii ) to study the
effect of
IGF-I on
vitamin D receptor (VDR) expression on 1 alpha, 25 ( OH ) 2D3 stimulated growth parameters and on AP activity