Gene interactions and pathways from curated databases and text-mining

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IGF1 — VDR

Text-mined interactions from Literome

Pirskanen et al., Eur J Biochem 1993 (Osteosarcoma) : The binding of the vitamin-D receptor (VDR) to its cognate response element is not affected by IGF-I
Klaus et al., Kidney Int 1998 : The studies were undertaken to investigate interaction between these two hormone systems, that is, ( i ) to study effects of 1 alpha, 25 ( OH ) 2D3 on IGF-type 1 receptors ( IGFIR ), on IGF-I stimulated cell replication, colony formation, and on alkaline phosphatase activity ( AP ), and conversely, ( ii ) to study the effect of IGF-I on vitamin D receptor (VDR) expression on 1 alpha, 25 ( OH ) 2D3 stimulated growth parameters and on AP activity