Gene interactions and pathways from curated databases and text-mining

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AKT1 — VAV1

Text-mined interactions from Literome

Hebeis et al., Blood 2005 : Likewise, activation of Akt ( a PI3K [ phosphatidylinositol 3-kinase ] target ) and phosphorylation of IkappaBalpha in response to CD180 or LPS required Vav1 and Vav2, while Vav1 deficiency led to defective responses to CD180
Miranti et al., Curr Biol 1998 : Additionally, Syk and Vav1 cooperatively induced activation of Jun N-terminal kinase (JNK), extracellular-signal regulated kinase 2 ( ERK2 ) and the kinase Akt , and phosphorylation of the oncoprotein Cbl in fibrinogen-adherent cells