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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to AKT1

AKT1 — VAMP2

Pathways - manually collected, often from reviews:

  • WikiPathways Insulin Signaling: GSK3B/AKT2/AKT1/SGK3/SGK1/GSK3A/PDPK1/SGK2 → STXBP2/CYTH3/KIF5B/EHD2/ARF6/RAB4A/CAP1/STXBP1/CRK/STXBP4/TBC1D4/SH2B2/EHD1/ARHGAP33/STX4/SNAP25/RHOQ/SNAP23/CBLB/STXBP3/CBL/FLOT2/CBLC/MYO1C/RHOJ/SORBS1/ARF1/RAPGEF1/VAMP2/FLOT1/KIF3A (activation)

Text-mined interactions from Literome

Lin et al., J Cell Physiol 2011 : Akt phosphorylation is necessary for the promoting effects of T3 on insulin stimulated VAMP2 translocation
Cheng et al., Proc Natl Acad Sci U S A 2012 (Diabetes Mellitus, Type 2) : APPL1 potentiates insulin secretion in pancreatic ß cells by enhancing protein kinase Akt dependent expression of SNARE proteins in mice