Gene interactions and pathways from curated databases and text-mining

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MAPK14 — TXN

Text-mined interactions from Literome

Kunchithapautham et al., Infect Immun 2003 : Overexpression of Bm-TRX-1 in a human monocyte cell line negatively regulated tumor necrosis factor alpha induced p38 mitogen activated protein kinase activity, suggesting a possible role of the 16-kDa Bm-TRX-1 in immunomodulation
Hsieh et al., FASEB J 2006 (MAP Kinase Signaling System) : Thioredoxin-ASK1 complex levels regulate ROS mediated p38 MAPK pathway activity in livers of aged and long lived Snell dwarf mice
Limón-Pacheco et al., Free Radic Biol Med 2007 (MAP Kinase Signaling System) : A time related GSH depletion in the liver and kidney correlated with p38 ( MAPK ) phosphorylation and induction of thioredoxin 1 (Tx-1) transcription
Li et al., Biochem Biophys Res Commun 2009 : Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose treated endothelial cells
Yang et al., Microbes Infect 2010 : Japanese encephalitis virus down-regulates thioredoxin and induces ROS mediated ASK1-ERK/p38 MAPK activation in human promonocyte cells
Ren et al., FEBS Lett 2010 (MAP Kinase Signaling System) : Knockdown of TXNIP in MMCs reversed HG-induced reduction of TRX activity and inhibited HG-induced activation of p38 MAPK and increased synthesis of TGF-beta1 and fibronectin