Gene interactions and pathways from curated databases and text-mining

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HIF1A — TWIST1

Text-mined interactions from Literome

Yang et al., Nat Cell Biol 2008 (Neoplasm Metastasis...) : Direct regulation of TWIST by HIF-1alpha promotes metastasis
Sun et al., Kidney Int 2009 (Anoxia) : Hypoxia-inducible factor-1alpha induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition ... These studies suggest that HIF-1alpha induces Twist expression in hypoxic tubular cells and that this plays a role in EMT during renal fibrogenesis
Cane et al., Cell Microbiol 2010 : Using RNA interference we show that bacteria induced HIF-1alpha regulates the expression of IL-8, VEGF and Twist1 , thereby pointing to a role for HIF-1 in angiogenesis and inflammation