Gene interactions and pathways from curated databases and text-mining

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IGF1 — TSC2

Text-mined interactions from Literome

Miyazaki et al., FEBS J 2010 : IGF-1 stimulated TSC1/TSC2 phosphorylation and redistribution were completely prevented by the phosphoinositide 3-kinase inhibitor wortmannin, but were not with the downstream mTOR inhibitor, rapamycin
Crossland et al., Am J Physiol Endocrinol Metab 2013 : However, binding of FAK to TSC2 or its phosphatase Shp-2 was not affected by IGF-I or cell phenotype