Gene interactions and pathways from curated databases and text-mining

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AKT1 — TRIM72

Text-mined interactions from Literome

Lee et al., Cell Death Differ 2010 : Because TRIM72 promoter analysis shows that two proximal E-boxes in TRIM72 promoter were essential for MyoD- and Akt dependent TRIM72 transcription, we can conclude that TRIM72 is a novel antagonist of IRS-1, and is essential as a negative regulator of IGF induced muscle differentiation
Ham et al., Exp Cell Res 2013 (Cardiomegaly...) : TRIM72 specifically regulated IGF-1 dependent AKT-mTOR signaling, resulting in a reduction of the size of cardiomyocytes