Gene interactions and pathways from curated databases and text-mining

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CASP7 — TRAF6

Text-mined interactions from Literome

Hull et al., J Immunol 2002 : LPS induced loss of mitochondrial transmembrane potential, cytochrome c release, and caspase activation are all blocked by TRAF6-C
Conti et al., J Neurosurg 2005 (Brain Neoplasms...) : The authors investigated the expression of NF-kappaB, caspase 3, TRAF1, TRAF2, and TRAF associated NF-kappaB activator/TRAF interacting protein ( TANK/I-TRAF ), a regulator of TRAF activity, in human gliomas
Georgopoulos et al., Cell Death Differ 2006 (Urologic Neoplasms) : Thus, TRAF3 stabilization, JNK activation and caspase-9 induction define a novel pathway of CD40 mediated apoptosis in carcinoma cells
Zhong et al., Tumour Biol 2013 (Adenocarcinoma...) : At the same time, we explored the effects of TRAF6 on the expression of the following proteins : phosphor-NF-?B ( p-p65 ), cyclin D1, caspase-3 , and matrix metalloproteinase 9 (MMP9) ... Downregulation of TRAF6 could decrease the expression of p-p65, cyclin D1, and MMP9 and increase the expression of caspase-3
Peng et al., Mol Cell Biochem 2013 (Glioma) : In addition, the effects of TRAF6 on the expression of phosphor-NF-?B ( p-p65 ), cyclin D1, caspase 3, and MMP-9 were also probed