Gene interactions and pathways from curated databases and text-mining

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AKT1 — TNFRSF1B

Text-mined interactions from Literome

Roux et al., J Biol Chem 2001 : Surprisingly, p75NTR increased , rather than decreased, Akt phosphorylation in a variety of cell types, including human Niemann-Pick fibroblasts, which lack acidic sphingomyelinase activity
Roux et al., Prog Neurobiol 2002 : p75NTR has been shown to activate the NF-kappaB, Akt , and JNK pathways and interacts with several adaptor proteins
Lim et al., FEBS Lett 2006 : CpG ODN induced the phosphorylation of Akt, and the inhibition of Akt by LY294002 suppressed CpG ODN induced TNF-alpha, TNFR-II , and MMP-9 expressions
Zhang et al., Journal of molecular cell biology 2013 (Encephalomyelitis, Autoimmune, Experimental...) : The inhibition of iTreg differentiation by TNF-a is mediated through a signaling cascade involving the induction of TNF receptor II (TNFR2) expression and the activation of Akt