Gene interactions and pathways from curated databases and text-mining

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CASP7 — TNFRSF10B

Text-mined interactions from Literome

Earel et al., Cancer Res 2006 (Urinary Bladder Neoplasms) : The increased TRAIL-R2 levels also resulted in accelerated death inducing signaling complex ( DISC ) formation, caspase activation, and loss of mitochondrial membrane potential, which all contributed to the increase in tumor cell death
Mazumdar et al., PloS one 2012 : Gelsolin modulation of cell death using this fragment involved upregulation of TRAIL-R1 and TRAIL-R2 , and involved caspase 3 activation by extrinsic pathway