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CASP7 — TNFRSF10B
Text-mined interactions from Literome
Earel et al., Cancer Res 2006
(Urinary Bladder Neoplasms) :
The increased
TRAIL-R2 levels also
resulted in accelerated death inducing signaling complex ( DISC ) formation,
caspase activation, and loss of mitochondrial membrane potential, which all contributed to the increase in tumor cell death
Mazumdar et al., PloS one 2012
:
Gelsolin modulation of cell death using this fragment involved upregulation of TRAIL-R1 and
TRAIL-R2 , and
involved caspase 3 activation by extrinsic pathway