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NOTCH4 — TNF

Pathways - manually collected, often from reviews:

• WikiPathways Notch Signaling Pathway: APH1A/APH1B/TNF/PSEN1/PSEN2/NCSTN → NOTCH2/NOTCH3/NOTCH4/NOTCH1 (activation)
  

Text-mined interactions from Literome

Ando et al., Oncogene 2003 (Arthritis, Rheumatoid) : We found that TNF induced the expression of Notch-1, Notch-4 , and Jagged-2 in RSF
Quillard et al., Arterioscler Thromb Vasc Biol 2008 (Coronary Artery Disease) : We found that inhibition of Notch activity, reflected by both a reduced CBF1 activity and Hes1 expression, parallels the downregulation of Notch4 expression mediated by TNF in ECs
Jiao et al., Clin Dev Immunol 2012 (Arthritis, Rheumatoid) : The aim of this paper was to investigate whether Notch signaling mediated TNF-a induced cytokine production of cultured fibroblast-like synoviocytes ( FLSs ) from RA