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EIF4E — TNF

Text-mined interactions from Literome

Plaisance et al., Am J Physiol Endocrinol Metab 2008 : TNF-alpha activated two signaling cascades : 1 ) ERK1/2 and its target eIF4E and 2 ) Akt and its downstream effectors GSK-3, p70 ( S6K ), and 4E-BP1 ... PD-98059 pretreatment abolished TNF-alpha induced phosphorylation of ERK1/2 and eIF4E , whereas PS was only partially inhibited
Marino et al., Proc Natl Acad Sci U S A 1989 (Uterine Cervical Neoplasms) : Tumor necrosis factor induces phosphorylation of a 28-kDa mRNA cap binding protein in human cervical carcinoma cells ... Thus, TNF-alpha stimulates the phosphorylation of this mRNA cap binding protein , which may be involved in the transduction of TNF-alpha-receptor binding into cellular responses