Gene interactions and pathways from curated databases and text-mining

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AKT1 — TLR9

Text-mined interactions from Literome

Dragoi et al., EMBO J 2005 : DNA-PKcs, but not TLR9 , is required for activation of Akt by CpG-DNA
Miller et al., Arterioscler Thromb Vasc Biol 2005 (Atherosclerosis) : In turn, TLR4 regulated phosphorylation of ERK1/2 but not of Akt , suggesting that mmLDL induced PI3K activation is TLR4 independent
Lim et al., FEBS Lett 2006 : Activation of toll-like receptor-9 induces matrix metalloproteinase-9 expression through Akt and tumor necrosis factor-alpha signaling
Santos-Sierra et al., EMBO J 2009 : In contrast to TLR2/6, TLR2/1 does not require Mal or MyD88 for Akt phosphorylation
Panigrahi et al., Circ Res 2013 (Disease Models, Animal...) : Platelet activation by TLR9 ligands induces IRAK1 and AKT phosphorylation, and it is Src kinase dependent