◀ Back to STAT3
STAT3 — TLR4
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Fukuzono et al., Arch Biochem Biophys 2010
:
G-CSF mediated
STAT3 phosphorylation and
inhibition of
TLR agonist induced cytokine production were prevented by pretreatment of cells with AG-490 ( JAK2 inhibitor )
Wang et al., PloS one 2010
(Reperfusion Injury) :
TLR4 inhibits mesenchymal stem cell (MSC)
STAT3 activation and thereby exerts deleterious effects on MSC mediated cardioprotection
Tel et al., Cancer Immunol Immunother 2012
:
Furthermore, oxaliplatin decreased
TLR induced STAT1 and
STAT3 expression, and NF-?B mediated responses
Ochi et al., J Clin Invest 2012
(Carcinoma, Pancreatic Ductal...) :
Furthermore,
TLR7 ligation
induced STAT3 activation and interfaced with Notch as well as canonical NF-?B and MAP kinase pathways, but downregulated expression of Notch target genes