Gene interactions and pathways from curated databases and text-mining

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TLR2 — WNT11

Text-mined interactions from Literome

Bansal et al., J Biol Chem 2011 (Bacterial Infections) : Interestingly, inducible NOS (iNOS) activity is pivotal for TLR2 mediated activation of Wnt-ß-catenin signaling as iNOS ( -/- ) mice demonstrated compromised ability to trigger activation of Wnt-ß-catenin signaling as well as Notch1 mediated cellular responses
Yi et al., PloS one 2012 : With respect to mechanism, TLR4 suppressed Wnt signaling, decreased phosphorylation and activation of the Wnt receptor LRP6, and blocked the protective effect of the Wnt3a ligand