Gene interactions and pathways from curated databases and text-mining

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NOS1 — TIMP1

Text-mined interactions from Literome

Eagleton et al., J Surg Res 2002 : This study tested the hypothesis that nitric oxide synthase (NOS) inhibition in whole aortic wall causes increases in cytokine stimulated MMP and TIMP expression
Lukivskaya et al., Eur J Clin Invest 2008 (Disease Models, Animal...) : Both NOS inhibitors up-regulated procollagen alpha1 ( I ), MMP-13, TIMP-1 and PAI-1 mRNA expression
Yuan et al., PloS one 2013 (Intervertebral Disc Degeneration) : ET-1 increased production of MMP-1 and MMP-13, decreased TIMP-1 production, and induced NO and NOS release by cultured CECs