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IGF2 — TGFB1
Text-mined interactions from Literome
Edmondson et al., J Cell Physiol 1999
:
Expression of
insulin-like growth factor binding protein-3 ( IGFBP-3 ) in human keratinocytes is
regulated by EGF and
TGFbeta1
Wolf et al., Neuroscience 1999
:
In the presence of fibroblast growth factor-2 and
insulin-like growth factor-II ,
transforming growth factor-beta1 ( 0.08 nM )
reduced 5-bromo-2'-deoxyuridine labeling by about 50 %, without interfering with chromaffin cell survival or death
Dahiya et al., Int J Impot Res 1999
(Erectile Dysfunction) :
The results of these experiments suggest that : ( 1 ) young and old rat penile tissues expressed mRNA transcripts for TGF alpha, TGF beta 1, TGF beta 2, TGF beta 3, IGF and NGF ; ( 2 )
TGF beta 1 gene expression was significantly
increased in old rat penile tissues as compared to young ; ( 3 ) mRNA transcripts for NGF and TGF beta 3 were significantly lower in old rat penile tissues as compared to young ; and ( 4 ) TGF alpha, TGF beta 2 and
IGF mRNA expression did not change in young and old rat penile tissues
Gray et al., Exp Cell Res 1999
(Carcinoma, Hepatocellular...) :
IGF-II enhances trichostatin A-induced
TGFbeta1 and p21 ( Waf1,Cip1, sdi1 ) expression in Hep3B cells
Ghahary et al., Growth Factors 2000
:
Mannose-6-phosphate/IGF-II receptors
mediate the effects of IGF-1 induced latent
transforming growth factor beta 1 on expression of type I collagen and collagenase in dermal fibroblasts
Dahlfors et al., Endocrinology 2000
:
Vascular endothelial growth factor and
transforming growth factor-beta1 regulate the expression of
insulin-like growth factor binding protein-3, -4, and -5 in large vessel endothelial cells
Villevalois-Cam et al., J Hepatol 2003
:
The hepatocyte is a direct target for
transforming-growth factor beta activation via the
insulin-like growth factor II/mannose 6-phosphate receptor
Scharf et al., Horm Metab Res 2003
(Carcinoma, Hepatocellular...) :
Finally, defective functions of the IGF-II/mannose 6-phosphate receptor involved in degradation of
IGF II , the
activation of the growth inhibitor
TGF-beta1 , and the lysosomal targeting of cathepsin proteases capable to degrade extracellular matrix proteins may contribute to the development of HCC
Zarzyńska et al., J Dairy Res 2005
:
Exogenous TGF-beta1,
IGF-I , EGF and GH
inhibited FBS-deficiency stimulated
TGF-beta1 expression
Ilvesmäki et al., J Endocrinol 1993
:
Transforming growth factor-beta 1 inhibited
IGF-II mRNA accumulation to the same extent as TPA
Lahm et al., Biochem Biophys Res Commun 1996
(Colorectal Neoplasms) :
Differential
effect of interleukin-4 and
transforming growth factor beta 1 on expression of proto-oncogenes and autocrine
insulin-like growth factor II in colorectal carcinoma cells
Hembree et al., J Anim Sci 1996
:
Cultured porcine myogenic cells produce
insulin-like growth factor binding protein-3 ( IGFBP-3 ) and
transforming growth factor beta-1 stimulates IGFBP-3 production
Rydziel et al., Endocrinology 1996
:
In conclusion, normal Ob cells express the PDGF-B gene, and
TGF beta 1 induces its transcription, whereas bFGF,
IGF-I , and PDGF-BB do not enhance the levels of PDGF-B mRNA
Gangji et al., Endocrinology 1998
:
We also determined mechanisms involved in the
regulation of
IGF-II by platelet derived growth factor (PDGF) BB, fibroblast growth factor-2 (FGF-2), and
transforming growth factor (TGF) beta1
Lacroix et al., Cancer Lett 1998
(Breast Neoplasms) :
The production of Il-11 was
increased by
transforming growth factor-beta1 in a dose dependent manner with a rapid ( 2 h ) and transient ( 24 h ) mRNA induction, but not by epidermal growth factor,
insulin-like growth factor-I and -II , basic fibroblast growth factor, platelet derived growth factor or parathyroid hormone