Gene interactions and pathways from curated databases and text-mining

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MAPK3 — TECR

Text-mined interactions from Literome

Becker et al., Am J Physiol Lung Cell Mol Physiol 2001 : Inhibition of tyrosine kinase, phosphoinositol 3-kinase, or p38 MAPK significantly attenuated VEGF mediated TER , F-actin remodeling, and chemotaxis ... VEGF mediated decreased TER was also significantly attenuated by inhibition of ERK1/2 MAPK but not by inhibition of fetal liver kinase-1 (flk-1) or Src kinase
Kiely et al., Kidney Int 2003 (MAP Kinase Signaling System) : The role of the ERK 1/2 and the p38 MAPK pathways in modulating TER was investigated using the inhibitors PD98059 and U0126 for ERK 1/2 and SB203580 for p38
Gonzalez et al., Free Radic Biol Med 2009 (MAP Kinase Signaling System) : An initial drop in TER at 6 h was followed by a significant increase at 24 h. Inhibition of ERK-1/2 activation attenuated the increase in TER observed at 24 h. Expression of occludin initially decreased, followed by partial recovery at 24 h