Gene interactions and pathways from curated databases and text-mining

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CREB1 — TCF7

Text-mined interactions from Literome

Riccio et al., Science 1999 : Together, these data support a model in which neurotrophins promote survival of neurons, in part through a mechanism involving CREB family transcription factor dependent expression of genes encoding prosurvival factors
Kelly et al., Hippocampus 2000 : Recent evidence indicated that the increase in protein synthesis may be cAMP dependent and that subsequent activation of the transcription factor , CREB , represented one step in the cascade of events leading to protein synthesis
Frissora et al., Eur J Immunol 2003 : IFN-gamma mediated inhibition of antigen receptor induced B cell proliferation and CREB-1 binding activity requires STAT-1 transcription factor
Chen et al., Mol Psychiatry 2006 : Enhanced hippocampal response to stress during development, and particularly the activation of the transcription factor CREB , may contribute to the enduring effects of stress during this period on hippocampal function
Ren et al., Genomics 2009 : Mutagenesis and cotransfection experiments showed that PKA regulation of this c-fos intronic element was mediated by two adjacent CRE-like sequences and the transcription factor CREB
Estrada et al., Frontiers in systems neuroscience 2009 : We hypothesized that fasting induced enhancement of synaptic plasticity was mediated by the increased signaling mediated by CREB ( cAMP response element binding protein ), an important nuclear protein and the transcription factor that is involved in the consolidation of memories in the hippocampus
Shanware et al., PloS one 2010 : Conserved and distinct modes of CREB/ATF transcription factor regulation by PP2A/B56gamma and genotoxic stress
Melnikova et al., PloS one 2010 (Disease Progression...) : Loss of AP-2alpha expression in metastatic melanoma occurs via a dual mechanism involving binding of CREB to the AP-2alpha promoter and CREB induced overexpression of another oncogenic transcription factor , E2F-1
Tong et al., J Neurosci 2012 : Using rat organotypic hippocampal cultures, we found that IL-1ß suppressed BDNF dependent regulation of Arc and phosphorylation of cofilin and cAMP response element binding protein ( CREB ), a transcription factor regulating Arc expression
Konradi et al., J Neurosci 1994 : Here we report that amphetamine induces phosphorylation of transcription factor cAMP response element binding protein ( CREB ) in rat striatum in vivo and that dopamine D1 receptor stimulation induces phosphorylation of CREB within specific complexes bound to cAMP regulatory elements
Suire et al., Eur J Biochem 1996 : Since we observed important dissociation kinetics, we hypothesized that the binding of CREB to the PRII site is stabilized by CREB binding protein (CBP) or by chicken-ovalbumin-upstream-promoter transcription factor ( COUP-TF ) binding to PRI site near to PRII
Rajadhyaksha et al., Dev Neurosci 1998 : One route to neuroplasticity involves activation of the transcription factor cyclic 3 ', 5'-adenosine monophosphate ( cyclic AMP ) response element binding protein ( CREB ) by phosphorylation of the amino acid 133Ser. Dopamine and glutamate, the two predominant neurotransmitters in the striatum, induce CREB phosphorylation in primary cultures of rat striatum through cyclic AMP and Ca2+ pathways