Gene interactions and pathways from curated databases and text-mining

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EPO — TCF24

Text-mined interactions from Literome

Tang et al., Biochem J 1999 (Anemia) : Mitogen activated protein kinase mediates erythropoietin induced phosphorylation of the TAL1/SCL transcription factor in murine proerythroblasts
Ogilvie et al., J Biol Chem 2000 : In erythroid progenitor cells, Epo stimulates induction of transcription factor GATA-1 and EpoR ; in C2C12 cells, GATA-3 and EpoR expression are induced
Andrassy et al., Clin Nephrol 2002 (Anemia...) : The aim of this study was to determine the effect of rh-EPO on the redox-sensitive transcription factor ( NF-kappaB ) in vivo and in vitro
Johnston et al., Mol Ther 2003 (beta-Thalassemia) : Specifically, expression of Epo was dependent on the presence of a chimeric transcription factor that is activated by the orally available small molecule drug rapamycin
Diensthuber et al., Otol Neurotol 2007 (Disease Progression...) : Erythropoietin expression is regulated by the transcription factor , HIF-1alpha
van Wijk et al., Haematologica 2010 (Polycythemia) : The ERYTHROPOIETIN (EPO) gene is regulated by the transcription factor Hypoxia Inducible Factor-alpha ( HIF-alpha )
Frede et al., Blood 2011 : SiRNA treatment revealed that the expression of EPO was largely dependent on the activation of the transcription factor complex HIF-2
Chrétien et al., EMBO J 1996 (Leukemia, Erythroblastic, Acute) : Stimulation by Epo induced an impaired activation of the STAT5 transcription factor in these cells