Gene interactions and pathways from curated databases and text-mining

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NOTCH4 — TBX6

Text-mined interactions from Literome

White et al., Genesis 2005 : Regulation of Tbx6 expression by Notch signaling
Yasuhiko et al., Proc Natl Acad Sci U S A 2006 : Tbx6 directly binds to the Mesp2 gene upstream region and mediates Notch signaling, and subsequent Mesp2 transcription, in the anterior presomitic mesoderm ... Our data therefore reveal that a mechanism, via Tbx6 dependent Notch signaling, acts on the transcriptional regulation of Mesp2
Yasuhiko et al., Development 2008 : In cultured cells, Tbx6 binding to the Mesp2 enhancer region is essential for the activation of Mesp2 by Notch signaling