Gene interactions and pathways from curated databases and text-mining

◀ Back to SIRT1

SIRT1 — STK11

Text-mined interactions from Literome

Peng et al., J Gastrointest Surg 2010 (Disease Models, Animal...) : LKB1 phosphorylates AMPK and may activate SIRT1
Morales-Alamo et al., J Appl Physiol 2012 (Acute Disease...) : This could have led to lower liver kinase B1 (LKB1) activation by SIRT1 and, hence, blunted Thr ( 172 ) -AMPKa phosphorylation ... Collectively, our results indicate that the signaling response to sprint exercise in human skeletal muscle is altered in severe acute hypoxia, which abrogated Thr ( 172 ) -AMPKa phosphorylation, likely due to lower LKB1 activation by SIRT1