Gene interactions and pathways from curated databases and text-mining

◀ Back to CREB1

CREB1 — SST

Text-mined interactions from Literome

Masson et al., Mol Cell Biol 1992 : Since overexpression of exogenous cPKA and CREB is sufficient to activate the somatostatin promoter in undifferentiated cells, these findings suggest that a negative factor ( s ) represses endogenous cPKA and CREB ... Thus, despite coregulation during differentiation and the ability to bind CREB, the somatostatin and VIP promoters are not coordinately activated by CREB in undifferentiated F9 cells
Leonard et al., Proc Natl Acad Sci U S A 1992 : DNA binding and functional analyses indicate that the cAMP-responsive factor CREB regulates somatostatin expression in these cells without requirement for phosphorylation at the protein kinase A-regulated Ser-133 phosphorylation site
Somvanshi et al., Int J Cardiol 2013 (Cardiomegaly) : SST enhances ß2AR agonist formoterol mediated effects on PKA, CREB and ERK1/2 phosphorylations whereas it inhibits isoproterenol mediated ERK1/2 and p38 signaling in concentration dependent manner