Gene interactions and pathways from curated databases and text-mining

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MAPK6 — SPHK1

Text-mined interactions from Literome

Cheon et al., Biochem Biophys Res Commun 2008 : As a result, inhibition of SPHK by SKI blocked phosphorylation of p38 MAPK , showing that SPHK activation by IL-18 is an upstream signal of p38 MAPK activation
Prakash et al., PloS one 2010 (Mycobacterium Infections, Nontuberculous) : In addition, our results also unraveled a novel regulation of p38MAPK by SphK-1 during M. smegmatis infection and generation of NO in macrophages