Gene interactions and pathways from curated databases and text-mining

◀ Back to STAT3

SP3 — STAT3

Text-mined interactions from Literome

Loeffler et al., Int J Cancer 2005 (Glioblastoma) : Interestingly, preincubation with STAT3 antibody prevented the binding of Sp1 and Sp3 to the -88/-50 element, indicating that STAT3 is involved in IL-6-driven Sp1/Sp3 protein-DNA complex formation
Su et al., Am J Physiol Cell Physiol 2009 : Cell confluency induced Stat3 activation regulates NHE3 expression by recruiting Sp1 and Sp3 to the proximal NHE3 promoter region during epithelial dome formation ... Thus, during confluency, ligand independent Stat3 activation leads to its interaction with Sp1/Sp3 , their recruitment to the SpA/B/C cluster in a Stat3 DNA binding domain dependent fashion, increased transcription, and expression of NHE3, to coordinate cell density mediated epithelial dome formation