◀ Back to QRICH2

QRICH2 — SP1

Text-mined interactions from Literome

Brasse-Lagnel et al., J Biol Chem 2003 : Electrophoretic mobility shift assays using either the Sp1 consensus sequence or an appropriate fragment of the ASS promoter sequence as a probe demonstrated that both glutamine and glucosamine increased Sp1 DNA binding ... Again, the effect of glutamine on Sp1 was inhibited by the addition of DON but not of glucosamine
Brasse-Lagnel et al., FEBS J 2007 : The inhibition was exerted at the level of the transcription factors Sp1 and nuclear-kappaB : ( a ) interleukin-1beta inhibited the glutamine stimulated DNA binding of Sp1 , which might be related to a decrease of its glutamine induced O-glycosylation, and ( b ) glutamine induced per se a decrease in the amount of nuclear p65 protein without affecting the stimulating effect of interleukin-1beta on nuclear factor-kappaB, which might be related to the metabolism of glutamine into glutamate