Gene interactions and pathways from curated databases and text-mining

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PPP2CA — SP1

Text-mined interactions from Literome

Lacroix et al., J Biol Chem 2002 : Sp1 dephosphorylation is likely to increase its transcriptional activity because PP2A overexpression potentiated Sp1 site-driven chloramphenicol acetyltransferase expression in dividing Kit225 T cells and okadaic acid reversed this effect
Cieslik et al., J Biol Chem 1998 : These results suggest that lyso-PC up-regulates eNOS transcription by a PP2A dependent increase in Sp1 binding activity