Gene interactions and pathways from curated databases and text-mining

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AKT1 — SOD1

Text-mined interactions from Literome

Abid et al., J Biol Chem 2004 : In contrast, VEGF mediated induction of Mn-SOD was enhanced by the phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 and by dominant negative Akt and was decreased by constitutively active Akt
Ichihara et al., Biochem Biophys Res Commun 2007 (Ventricular Dysfunction, Left) : Both drugs also inhibited the activation of the transcription factor NF-kappaB and increase in lipid peroxidation in the left ventricle induced by DOX, whereas only PEG-SOD inhibited the DOX induced activation of Akt and Akt regulated gene expression
Florczak et al., Radiother Oncol 2009 (Adenocarcinoma...) : Applying Western blotting, the pattern of radiation induced SOD expression and activation of Akt as well as DNA-PKcs was analyzed
Zhang et al., J Cell Biochem 2012 : Further, phosphatidylinositol 3-kinase (PI3K)/protein kinase B ( PKB, Akt ) contributed to the ARE-driven Mn SOD expression