Gene interactions and pathways from curated databases and text-mining

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MAPK14 — SOAT1

Text-mined interactions from Literome

Kawamata et al., Int J Oncol 1999 (Urinary Bladder Neoplasms) : These results suggest that i ) EGF inhibits the growth of T24 cells via induction of p21waf1 mediated by STAT, and ii ) the balance between the STAT induced p21waf1 and MAPK activities regulates the growth of human bladder cells after EGF treatment
Kamimura et al., Rev Physiol Biochem Pharmacol 2003 (Acute-Phase Reaction...) : Intriguingly, recent in vivo studies indicated that the SHP-2 binding site- and YXXQ mediated pathways through gp130 are not mutually exclusive but affect each other : a mutation at the SHP-2 binding site prolongs STAT3 activation, and a loss of STAT activation by gp130 truncation leads to sustained SHP-2/ERK MAPK phosphorylation
Rychli et al., Journal of thrombosis and haemostasis : JTH 2010 : Oncostatin M (OSM) increased Ang2 expression in human umbilical vein endothelial cells via Janus kinase/signal transducer and activator of transcription ( JAK/STAT ) and mitogen activated protein ( MAP ) kinase activation
Pratt et al., J Biol Chem 1996 : Several downstream signaling events induced by GM-CSF stimulation have been described, including activation of tyrosine kinases and tyrosine phosphorylation of cellular proteins ( including beta c ) and activation of the Ras/mitogen activated protein kinase and the JAK/STAT pathways