Gene interactions and pathways from curated databases and text-mining

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IL22 — SOAT1

Text-mined interactions from Literome

Kotenko et al., J Biol Chem 2001 : Substitution of the CRF2-9 intracellular domain with the IFN-gammaR1 intracellular domain changes the pattern of IL-TIF induced Stat activation
Kotenko et al., J Immunol 2001 : In the presence of the IL-22BP, IL-22 is unable to induce Stat activation in IL-22-responsive human lung carcinoma A549 cells ... The addition of IL-22BP neutralizes the ability of IL-22 to induce Stat activation and MHC class I Ag expression in these cells
Brand et al., Am J Physiol Gastrointest Liver Physiol 2007 (Disease Models, Animal...) : Binding of IL-22 to its receptor complex expressed on human hepatic cells and primary human hepatocytes resulted in the activation of MAPKs, Akt, and STAT proteins ... SOCS-1/3 overexpression abrogated IL-22 induced STAT activation and decreased IL-22 mediated liver cell regeneration
Seidel et al., Proc Natl Acad Sci U S A 1995 (Carcinoma, Hepatocellular...) : We have systematically examined the effects of the spacing between the TT and AA core half sites on the binding of the STAT complexes activated by IFN-gamma, interleukin (IL) 6, granulocyte-macrophage colony stimulating factor, and IL-4