Gene interactions and pathways from curated databases and text-mining

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MAPK14 — SMN1

Text-mined interactions from Literome

Shen et al., Biochem Biophys Res Commun 2006 : Inhibiting p38MAPK with SB202190 or JNK with SP600125 also reduced angiotensin II-induced alpha-SMA expression
Vepachedu et al., J Immunol 2007 (MAP Kinase Signaling System...) : Blocking p38 MAPK resulted in reduced alpha-SMA expression by Unc119 suggesting that the p38 pathway regulates Unc119 induced myofibroblast differentiation
Ding et al., J Biol Chem 2008 (Disease Models, Animal...) : Although both ERK and p38 MAPK activation is required for maximal TGF-beta1 induced alpha-SMA expression, ERK is the major signaling intermediate in cells that express FAK
Pappas et al., Eur J Vasc Endovasc Surg 2009 (Chronic Disease...) : alpha-SMA protein expression in LC fibroblasts increased with MAPK inhibition with/without TGF-beta(1) stimulation, and correlated with the degree of gel contraction
Liu et al., Nan Fang Yi Ke Da Xue Xue Bao 2011 (Scleroderma, Systemic) : In the presence of TGF-ß ( 1 ), blocking of Smads, ERK/MAPK , and p38MAPK pathways, but not JNK/MAPK pathway, caused an obvious decrease in a-SMA levels in the fibroblasts in both groups