Gene interactions and pathways from curated databases and text-mining

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NOTCH4 — SMC3

Text-mined interactions from Literome

Proweller et al., J Biol Chem 2005 : Taken together, these results demonstrate that Notch signaling represses myocardin dependent SMC transcription
Morrow et al., Circ Res 2005 : Notch 3 receptor overexpression significantly reversed the strain induced changes in SMC proliferation and apoptosis to levels comparable to unstrained control cells, whereas Notch inhibition further potentiated the changes in SMC apoptosis and proliferation
Shin et al., Development 2009 : Notch activity in nascent ventral mesoderm cells promotes SMC progenitor formation and mediates the separation of SMC and BC/EC common progenitors marked by another bHLH factor, Scl
Morrow et al., Arterioscler Thromb Vasc Biol 2009 : The role of Notch in mediating hedgehog control of adult vascular smooth muscle cell ( SMC ) growth and survival remains unexplored
Li et al., Circulation 2009 : In SMCs derived from CHF1/Hey2-/- mice, activation of Notch signaling did not lead to increased SMC proliferation or migration