Gene interactions and pathways from curated databases and text-mining

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SMAD7 — STAT3

Text-mined interactions from Literome

Fukuda et al., Mol Cell Biol 2007 : Potentiation of astrogliogenesis by STAT3 mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells
Luwor et al., Oncogene 2013 (Neoplasms) : Here, we report that the tumor associated overexpression of epidermal growth factor receptor (EGFR) desensitizes TGF-ß signaling and its cytostatic regulation through specific and persistent Stat3 activation and Smad7 induction in vivo
Meisel et al., Immunity 2013 (Encephalomyelitis, Autoimmune, Experimental) : Furthermore, PKCa-deficient ( Prkca ( -/- ) ) cells demonstrated a defect in SMAD dependent IL-2 suppression, as well as decreased STAT3 DNA binding within the Il17a promoter