Gene interactions and pathways from curated databases and text-mining

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AKT1 — SLC2A4RG

Text-mined interactions from Literome

Cullen et al., Am J Physiol Gastrointest Liver Physiol 2004 : The role of cAMP-GEF and PKA on activation of Akt , a kinase implicated in cAMP survival signaling, was investigated
Wood et al., J Biol Chem 2006 : TcRzeta/CD3 and TcRzeta/CD3-CD28 signaling requires the guanine nucleotide exchange factor (GEF) Vav-1 as well as the activation of phosphatidylinositol 3-kinase, protein kinase B ( PKB/AKT ), and its inactivation of glycogen synthase kinase-3 ( GSK-3 )
Gates et al., Am J Physiol Gastrointest Liver Physiol 2009 : Maximal cAMP-GEF mediated Akt phosphorylation as well as protection from bile acid induced apoptosis requires activation of Src-TYK and the EGFR