Gene interactions and pathways from curated databases and text-mining

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SIRPA — TLR4

Text-mined interactions from Literome

Miyake et al., Genes Cells 2008 : The possible role of SHPS-1 in regulation of Toll-like receptor ( TLR ) -dependent production of proinflammatory cytokines by macrophages has remained unknown, however ... SHPS-1 then negatively regulates TLR4- or TLR3 dependent cytokine production through inhibition of NF-kappaB dependent signaling
Kim et al., Inflamm Res 2013 : In order to investigate the role of SHPS-1 in Toll-like receptor ( TLR ) -mediated activation, human monocytic cell lines were treated with anti-SHPS-1 monoclonal antibody