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MAPK3 — SIRPA

Text-mined interactions from Literome

Oh et al., Mol Cell Biol 1999 : Overexpression of SHPS-1 in 293 cells potentiated integrin induced mitogen activated protein kinase ( MAPK ) activation, and potentiation required functional SHP-2
Kontaridis et al., J Cell Sci 2001 : Inhibition of p38 MAPK by SB203580 in differentiating C2C12 myoblasts blocks MyoD expression, SHPS-1 tyrosyl phosphorylation and the association of SHPS-1 with SHP-2
Ruhul Amin et al., Oncogene 2002 : Exogenous expression of either SHPS-1 mutants that lack SHP-2 binding function or a dominant negative mutant of SHP-2 markedly inhibited the activation of Erk 1/2 and Akt by IL-1beta, whereas wild type SHPS-1 did not ... Taken together, our results strongly suggest that activation of Erk 1/2 and Akt by proinflammatory cytokines requires tyrosine phosphorylation of SHPS-1 and subsequent association of SHPS-1 with SHP-2
Kapoor et al., Cancer Res 2004 (Glioblastoma) : Interestingly, pharmacological inhibition of the kinase activities of EGFR, erbB2, and src and activation of mitogen activated protein kinase , but not phosphatidylinositol 3'-kinase, significantly up-regulated SIRPalpha1 promoter activity
Takada et al., J Biol Chem 1998 : The overexpression of wild-type SHPS-1 , but not of a mutant SHPS-1 in which all four tyrosine residues in its cytoplasmic region were mutated to phenylalanine, markedly enhanced insulin induced activation of mitogen activated protein kinase in Chinese hamster ovary cells that overexpress the human insulin receptor