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AKT1 — SHC1
Text-mined interactions from Literome
Baughn et al., J Virol 2005
(Cell Transformation, Viral) :
In contrast to effects on proliferation, survival of the cells and activation of
Akt were not
affected by expression of DN
Shc
Lockyer et al., J Immunol 2007
:
Restoring STAT5 activity via a heterologous receptor rescued
Shc induced
Akt/p70S6 kinase activity and cell proliferation with kinetics consistent with a transcriptional mechanism
Lee et al., J Biol Chem 2010
:
OSS induced activation of
PI3K/Akt/mTOR/p70S6K and cell proliferation were
inhibited by specific antibodies or small interference RNAs of alpha ( v ) beta ( 3 ) and beta ( 1 ) integrins and by dominant negative mutants of
Shc ( Shc-SH2 ) and focal adhesion kinase ( FAK ) ( FAK ( F397Y ) )