Gene interactions and pathways from curated databases and text-mining

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MAPK6 — SGK1

Text-mined interactions from Literome

Gonzalez-Robayna et al., Mol Endocrinol 2000 : In contrast, FSH induction and phosphorylation of Sgk protein requires A kinase ( H89 sensitive ) but also involves PI3-K ( LY294002 sensitive ) as well as p38MAPK ( SB203580 sensitive ) pathways
Meng et al., Am J Physiol Cell Physiol 2005 : Overexpression of p38alpha increased constitutive SGK phosphorylation at Ser78, whereas dominant negative p38alpha MAPK blocked IL-6 induced SGK phosphorylation and nuclear translocation
BelAiba et al., Circ Res 2006 (Hypertension, Pulmonary) : These data show that thrombin potently induces Sgk-1 involving NADPH oxidases, phosphatidylinositol 3-kinase, p38 mitogen activated protein kinase , and phosphoinositide dependent kinase-1, and that activation of nuclear factor kappaB by Sgk-1 mediates TF expression and activity by thrombin
Notch et al., Comp Biochem Physiol A Mol Integr Physiol 2012 : To test the hypothesis that mitogen activated protein kinase ( MAPK14 ) is responsible for the rise in SGK1 we identified the coding sequence of killifish MAPK14-1 and designed a translational blocking vivo-morpholino targeting MAPK14-1