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IL5 — SETBP1
Text-mined interactions from Literome
Smart et al., Clin Exp Allergy 2002
(Hypersensitivity) :
Symptomatic atopic children had reduced SEB induced IFN-gamma and increased
SEB induced IL-4 and
IL-5 as compared with non-atopic controls ... In contrast,
SEB induced IFN-gamma, IL-4 and
IL-5 production in asymptomatic atopics was not significantly different from the non-atopic control subjects
Matsui et al., J Interferon Cytokine Res 2004
(Dermatitis, Atopic) :
MDM inhibited
SEB induced mRNA expression of the Th2 cytokines interleukin-4 (IL-4) and
IL-5 in PBMCs from patients with AD
Rowe et al., J Allergy Clin Immunol 2004
(Genetic Predisposition to Disease...) :
In contrast, sensitization was strongly associated with polyclonal IFN-gamma responses to both PHA ( P=.002 ) and SEB ( P=.005 ), and also with
SEB induced
IL-5 ( P =.05 ), IL-10 ( P =.02 ), and IL-13 ( P =.01 )
Okano et al., J Allergy Clin Immunol 2009
(Eosinophilia...) :
PGE ( 2 ) significantly and dose-dependently inhibited
SEB induced
IL-5 , IL-13, and RANTES production by diclofenac treated DNPCs. E-prostanoid (EP) 2 receptor-selective agonist strongly inhibited the production of all 3 cytokines
Yu et al., American journal of rhinology & allergy 2009
(Chronic Disease...) :
Results indicate ( 1 ) stimulation of HNEC with
SEB resulted in increased
IL-5 and GM-CSF expression, which could be suppressed by dexamethasone ( p < 0.05 ), and SEB at concentrations of 1-100 ng/mL effectively promoted IL-5 and GM-CSF release by HNEC ( p < 0.05 ) ; ( 2 ) patients with CRSwNP showed a significantly increased expression of IL-5 and GM-CSF in HNEC than patients without CRSwNP ( p < 0.05 ) ; and ( 3 ) the expression of IL-5 and GM-CSF was significantly up-regulated under the stimulus of SEB compared with IL-1beta ( p < 0.05 )
Tan et al., American journal of rhinology & allergy 2009
(Asthma...) :
SEB alone
caused an increase in
IL-5 levels that could be dampened when CpG-ODN was added in combination with SEB ... Asthmatic and nonasthmatic patients present as two distinct categories as reflected by significant differences in their
IL-5 response to CpG-ODN ( F = 11.93 ; ***p = 0.0008 ),
SEB ( F = 41.34 ; *p = 0.0476 ) and CpG-ODN with SEB ( F = 13.2 ; *p = 0.0114 )
Hayworth et al., Clin Exp Immunol 2009
(Staphylococcal Infections) :
Here, we report that bovine LF ( bLF ) was indeed able to attenuate
SEB induced proliferation,
interleukin-2 production and CD25 expression by human leucocyte antigen ( HLA ) -DR4 transgenic mouse T cells
Higaki et al., Clin Exp Allergy 2012
(Eosinophilia...) :
LPS pre-treatment enhanced
SEB induced
IL-5 , IL-13 and IL-17A production in diclofenac treated DNPCs, while addition of PGE ( 2 ) inhibited IL-5, IL-13 and IFN-? production
Okano et al., Int Arch Allergy Immunol 2013
(Chronic Disease...) :
In addition, neutralization of IL-18 significantly suppressed
SEB induced
IL-5 , IL-13, and IFN-?, but not IL-17A production
Cardell et al., Eur J Immunol 1993
:
High frequencies of cells producing interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) were induced, but very low frequencies of CD4+ T cells produced IL-4,
IL-5 or IL-10 in
response to
SEB
König et al., Int Arch Allergy Immunol 1995
(Dermatitis, Atopic) :
In contrast to normal donors T cells from donors with AD predominantly express mRNA for IL-4,
IL-5 , and only diminished levels for IFN-gamma and IL-12 upon
stimulation with
SEB and SEA