Gene interactions and pathways from curated databases and text-mining

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SERPINF1 — STAT3

Text-mined interactions from Literome

Smith et al., J Urol 2008 (Prostatic Neoplasms) : Instead, PEDF activated in this order RhoA, nuclear factor kappaB and Stat3
Zheng et al., Invest Ophthalmol Vis Sci 2010 (Hyperglycemia) : HG exposure caused hyperpolarization of Deltapsim and increased ROS generation in BRECs ; meanwhile, like H ( 2 ) O ( 2 ), it also induced the phosphorylation of JAK2/STAT3 and increased VEGF expression ; these changes were inhibited by PEDF