Gene interactions and pathways from curated databases and text-mining

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CASP7 — SERPINF1

Text-mined interactions from Literome

Tan et al., Biochem Biophys Res Commun 2010 (Bone Neoplasms...) : In this report, pigment epithelium derived factor (PEDF) induced apoptosis in the chondrosarcoma cell line - JJ012, with upregulation of Bax, Fas, caspase-3 and -6 and downregulation of Bcl-2
Sheikpranbabu et al., Diabetes Metab 2011 (Diabetic Retinopathy) : In addition, PEDF inhibited AGE induced ROS generation by increasing levels of SOD and GSH, and also blocked the activation of caspase-3