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AKT1 — SDF4

Text-mined interactions from Literome

Zhou et al., J Biol Chem 2002 (Glioma...) : Furthermore, SDF-1 induced the phosphorylation of Akt ( protein kinase B ), a kinase associated with survival, and prevented the apoptosis of glioma cells when serum was withdrawn from the culture medium
Peng et al., J Neurosci Res 2004 : Moreover, SDF-1alpha induced increased NPCs levels of inositol 1,4,5-triphosphate, extracellular signal regulated kinases 1/2, Akt , c-Jun N-terminal kinase, and intracellular calcium whereas it diminished cyclic adenosine monophosphate
Basu et al., J Immunol 2007 : Concomitantly, SDF-1 induced Akt phosphorylation was robust and prolonged
Fuhler et al., Blood 2008 (MAP Kinase Signaling System...) : Furthermore, SDF-1 stimulated activation of Rac and the PI3K target protein kinase B is impaired in CD34 ( + ) cells from MDS patients
Shahabi et al., J Leukoc Biol 2008 : Western blots showed that SDF induced phospho- ( p ) -Akt [ threonine ( Thr ) 308 and serine 473 ], a proxy for PI3K activity, in fresh cells and p-PKC-theta in 48 h unstimulated cells
Oh et al., Biochem Biophys Res Commun 2010 (Myocardial Ischemia) : In addition, SDF-1alpha induced migration and ERK1/2, Akt , and eNOS activation were reduced by AMD3100, a CXCR4-specific peptide antagonist, or by siRNA-CXCR4