Gene interactions and pathways from curated databases and text-mining

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CXCR4 — SDF2

Text-mined interactions from Literome

Rempel et al., Clin Cancer Res 2000 (Astrocytoma...) : In tumors, SDF1 and CXCR4 expression was colocalized when both were expressed, and SDF1 and CXCR4 expression increased with increasing tumor grade ( from 0.5+ to 6+ )
Yuecheng et al., Eur J Cancer Prev 2007 (Neoplasm Invasiveness...) : In ovarian cancer cells, SDF-1 stimulation resulted in increased CXCR4 expression at both the transcription and protein levels
Taki et al., Oncol Rep 2008 (Carcinoma, Squamous Cell...) : Furthermore, SDF-1alpha and TGF-beta1 up-regulated the expression of CXCR4 and cell migratory activity in these cells
Tesio et al., Blood 2011 : Interestingly, stromal cell derived factor 1/CXC chemokine receptor-4 signaling induced hepatocyte growth factor production and c-Met activation
Olbrich et al., Gynecol Oncol 2010 (Bone Neoplasms...) : Furthermore, SDF-1 induced CXCR4 signaling was down-regulated
Fan et al., Inflammation 2012 (Disease Models, Animal...) : The chemokine CXC receptor 4 (CXCR4) is activated by stromal cell derived factor ( SDF-1a )