Gene interactions and pathways from curated databases and text-mining

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IL5 — SAA1

Text-mined interactions from Literome

Sasaki et al., J Med Microbiol 2001 (Streptococcal Infections) : Furthermore, a reverse transcription-PCR assay revealed that SAA 10 microg/ml could induce mRNA accumulation of tumour necrosis factor-alpha, interleukin (IL)-1beta and IL-6 as well as iNOS
Ribeiro et al., Mediators Inflamm 2003 : In a previous study, we reported that SAA induces the release of tumor necrosis factor-alpha, interleukin (IL)-1beta and IL-8 from human blood neutrophils
Thorn et al., Scand J Immunol 2004 : Here, we examine the roles of TNF-alpha, interleukin-6 (IL-6) and GCs on the transcriptional regulation of the two human A-SAA genes ( SAA1 and SAA2 ) and show that these stimuli have different effects on the SAA1 and SAA2 promoters in HepG2 hepatoma and KB epithelial cell lines
Rienhoff et al., Mol Biol Med 1990 (Amyloidosis...) : Studies in vitro and in vivo demonstrated that the expression of SAA genes is regulated by the inflammatory cytokine interleukin-1 ... Moreover, both the interleukin-1 induced expression and the enhanced liver-specific expression of the SAA gene are controlled by the binding of nuclear proteins to specific DNA sequences upstream from the structural gene
Mackiewicz et al., Biochem J 1988 : Comparison of these findings with those in human hepatoma cell lines, in which interleukin-1 does not induce serum amyloid A synthesis, suggests that the effect of interleukin-1 on serum amyloid A synthesis may be indirect
Weinstein et al., J Trauma 1987 (Acute-Phase Reaction...) : The effect of interleukin-1 on mouse liver serum amyloid A mRNA levels was investigated
Moshage et al., Biochem Biophys Res Commun 1988 : The effect of interleukin-1 , interleukin-6 and its interrelationship on the synthesis of serum amyloid A and C-reactive protein in primary cultures of adult human hepatocytes