Gene interactions and pathways from curated databases and text-mining

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S1PR1 — STAT3

Text-mined interactions from Literome

Lee et al., Nat Med 2010 (Neoplasms) : STAT3 induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
Liu et al., Blood 2012 (Disease Models, Animal...) : Inhibition of S1PR1 expression by shRNA in the lymphoma cells validates that blocking S1PR1 affects expression of STAT3 downstream genes critically involved in tumor cell survival, proliferation, tumor invasion, and/or immunosuppression