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S1PR1 — STAT3
Text-mined interactions from Literome
Lee et al., Nat Med 2010
(Neoplasms) :
STAT3 induced
S1PR1 expression is crucial for persistent STAT3 activation in tumors
Liu et al., Blood 2012
(Disease Models, Animal...) :
Inhibition of S1PR1 expression by shRNA in the lymphoma cells validates that blocking
S1PR1 affects expression of
STAT3 downstream genes critically involved in tumor cell survival, proliferation, tumor invasion, and/or immunosuppression